Detailed Description of Pharmacokinetic Simulators

Brief Manual

Pharmacokinetic Simulators

Model 1: Continuous IV Infusion

Model 2: Continuous IV Infusion with Distribution Phase

Model 3: Intermittent Administration

Model 4: Intermittent Administration with Absorption Phase

Model 5: Intermittent Administration with Distribution Phase

Model 6: Intermittent Administration with Absorption and Distribution Phases

Case Examples

Theophylline: Comparison of a continuous IV infusion with both intermittent IV and PO dosing

Pentobarital Infusion: Adjustable With Typical Starting Values

Thiopental: Comparison of a single IV bolus to a continuous infusion

Digoxin Pharmacokinetics

Tacrolimus: Adjustable With Typical Starting Values